2022 Lexus IS 350

used

Automatic

Silver exterior

$42,662

Jim Hudson Lexus

4.9

2022 Lexus IS 350 | used

$42,662

silver exterior, black interior

Automatic

Rear-wheel Drive

Jim Hudson Lexus

4.9

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2022 Lexus IS 350

used

Automatic

White exterior

$42,662

Jim Hudson Lexus

4.9

2022 Lexus IS 350 | used

$42,662

white exterior, white interior

Automatic

Rear-wheel Drive

Jim Hudson Lexus

4.9

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2025 Lexus IS 350

new

Unknown

Black exterior

$51,411

Jim Hudson Lexus

4.9

2025 Lexus IS 350 | new

$51,411

MSRP: $48,969

black exterior, circuit red nuluxe and black geometric trim interior

Unknown

Rear-wheel Drive

Jim Hudson Lexus

4.9

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2025 Lexus IS 350

new

Unknown

Red exterior

$51,947

Jim Hudson Lexus

4.9

2025 Lexus IS 350 | new

$51,947

MSRP: $49,505

red exterior, black nuluxe and black geometric trim interior

Unknown

Rear-wheel Drive

Jim Hudson Lexus

4.9

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2024 Lexus IS 350

used

Automatic

Infrared exterior

$45,389

Toyota of Rock Hill

4.7

2024 Lexus IS 350 | used

$45,389

infrared exterior, black interior

Automatic

Rear-wheel Drive

Toyota of Rock Hill

4.7

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2018 Lexus IS 350

used

Automatic

Nebula Gray Pearl exterior

$29,995

Audi Columbia

4.6

2018 Lexus IS 350 | used

$29,995

nebula gray pearl exterior, black interior

Automatic

Rear-wheel Drive

Audi Columbia

4.6

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2021 Lexus IS 350

used

Automatic

Red exterior

$37,704

Herlong Ford

4.6

2021 Lexus IS 350 | used

$37,704

red exterior, sport interior

Automatic

Rear-wheel Drive

Herlong Ford

4.6

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2022 Lexus IS 350

used

Automatic

Ultra White exterior

$41,500

Steve Padgett's Honda Of Lake Murray

4.6

2022 Lexus IS 350 | used

$41,500

ultra white exterior, black w/black interior

Automatic

Rear-wheel Drive

Steve Padgett's Honda Of Lake Murray

4.6

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2023 Lexus IS 350

used

Automatic

Atomic Silver exterior

$43,998

BMW Of Columbia

4.6

2023 Lexus IS 350 | used

$43,998

atomic silver exterior, circuit red interior

Automatic

Rear-wheel Drive

BMW Of Columbia

4.6

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2018 Lexus IS 350

used

Automatic

Gray exterior

$29,995

Jim Hudson Chevrolet

4.5

2018 Lexus IS 350 | used

$29,995

gray exterior, black interior

Automatic

Rear-wheel Drive

Jim Hudson Chevrolet

4.5

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2023 Lexus IS 350

used

Automatic

Maroon exterior

$47,995

Dick Smith Hyundai of Greenville

4.5

2023 Lexus IS 350 | used

$47,995

maroon exterior, black interior

Automatic

All-wheel Drive

Dick Smith Hyundai of Greenville

4.5

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2023 Lexus IS 350

used

Automatic

Ultra White exterior

$44,998

Lexus of Greenville

4.4

2023 Lexus IS 350 | used

$44,998

ultra white exterior, rioja red interior

Automatic

Rear-wheel Drive

Lexus of Greenville

4.4

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2024 Lexus IS 350

new

Automatic

Caviar exterior

$47,705

Lexus of Greenville

4.4

2024 Lexus IS 350 | new

$47,705

MSRP: $47,705

caviar exterior, rioja red nulux interior

Automatic

Rear-wheel Drive

Lexus of Greenville

4.4

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2025 Lexus IS 350

new

Automatic

Incognito exterior

$49,493

Lexus of Greenville

4.4

2025 Lexus IS 350 | new

$49,493

MSRP: $49,493

incognito exterior, circuit red nul interior

Automatic

Rear-wheel Drive

Lexus of Greenville

4.4

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2025 Lexus IS 350

new

Automatic

Incognito exterior

$50,063

Lexus of Greenville

4.4

2025 Lexus IS 350 | new

$50,063

MSRP: $50,063

incognito exterior, black nuluxe interior

Automatic

Rear-wheel Drive

Lexus of Greenville

4.4

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2025 Lexus IS 350

new

Automatic

Cloudburst Gray exterior

$52,463

Lexus of Greenville

4.4

2025 Lexus IS 350 | new

$52,463

MSRP: $52,463

cloudburst gray exterior, black nuluxe an interior

Automatic

Rear-wheel Drive

Lexus of Greenville

4.4

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2025 Lexus IS 350

new

Automatic

Caviar exterior

$52,623

Lexus of Greenville

4.4

2025 Lexus IS 350 | new

$52,623

MSRP: $52,623

caviar exterior, black interior

Automatic

Rear-wheel Drive

Lexus of Greenville

4.4

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2024 Lexus IS 350

new

Automatic

Cloudburst Gray exterior

$52,780

Lexus of Greenville

4.4

2024 Lexus IS 350 | new

$52,780

MSRP: $52,780

cloudburst gray exterior, circuit red w/black interior

Automatic

Rear-wheel Drive

Lexus of Greenville

4.4

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2025 Lexus IS 350

new

Automatic

Ultra White exterior

$52,793

Lexus of Greenville

4.4

2025 Lexus IS 350 | new

$52,793

MSRP: $52,793

ultra white exterior, black nuluxe an interior

Automatic

Rear-wheel Drive

Lexus of Greenville

4.4

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2025 Lexus IS 350

new

Automatic

Infra-Red exterior

$53,128

Lexus of Greenville

4.4

2025 Lexus IS 350 | new

$53,128

MSRP: $53,128

infra-red exterior, black nuluxe an interior

Automatic

Rear-wheel Drive

Lexus of Greenville

4.4

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2012 Lexus IS 350

used

Automatic

White exterior

$21,990

JT's Kia of Rock Hill

4.0

2012 Lexus IS 350 | used

$21,990

white exterior, n/a interior

Automatic

Rear-wheel Drive

JT's Kia of Rock Hill

4.0

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2023 Lexus IS 350

used

Automatic

Silver exterior

$37,401

Automaxx Of Summerville

2.7

2023 Lexus IS 350 | used

$37,401

silver exterior, circuit red interior

Automatic

All-wheel Drive

Automaxx Of Summerville

2.7

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2022 Lexus IS 350

used

Automatic

Silver exterior

$41,981

Automaxx Of Summerville

2.7

2022 Lexus IS 350 | used

$41,981

silver exterior, premium synthetic seats interior

Automatic

Rear-wheel Drive

Automaxx Of Summerville

2.7

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2020 Lexus IS 350

used

Automatic

Gray exterior

$34,998

CarMax Greenville

N/A

2020 Lexus IS 350 | used

$34,998

gray exterior, tan interior

Automatic

Rear-wheel Drive

CarMax Greenville

N/A

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2021 Lexus IS 350

used

Automatic

Atomic Silver exterior

$38,979

Pendarvis Chevrolet

N/A

2021 Lexus IS 350 | used

$38,979

MSRP: $42,085

atomic silver exterior, black interior

Automatic

Rear-wheel Drive

Pendarvis Chevrolet

N/A

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2023 Lexus IS 350

used

Automatic

Gray exterior

$42,998

CarMax

N/A

2023 Lexus IS 350 | used

$42,998

gray exterior, red interior

Automatic

Rear-wheel Drive

CarMax

N/A

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Lexus IS 350 vehicles for Sale in South Carolina

26 Results

2022 Lexus IS 350 | used

2022 Lexus IS 350 | used

2025 Lexus IS 350 | new

2025 Lexus IS 350 | new

2024 Lexus IS 350 | used

2018 Lexus IS 350 | used

2021 Lexus IS 350 | used

2022 Lexus IS 350 | used

2023 Lexus IS 350 | used

2018 Lexus IS 350 | used

2023 Lexus IS 350 | used

2023 Lexus IS 350 | used

2024 Lexus IS 350 | new

2025 Lexus IS 350 | new

2025 Lexus IS 350 | new

2025 Lexus IS 350 | new

2025 Lexus IS 350 | new

2024 Lexus IS 350 | new

2025 Lexus IS 350 | new

2025 Lexus IS 350 | new

2012 Lexus IS 350 | used

2023 Lexus IS 350 | used

2022 Lexus IS 350 | used

2020 Lexus IS 350 | used

2021 Lexus IS 350 | used

2023 Lexus IS 350 | used